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| Career Wins Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Wins | IP | Last Year | Single Season Leaderboard |
| 1. | Samson Steele | 21 | 266.0 | 2000 | |
| Jeffrey Cargo | 21 | 244.3 | 2000 | ||
| 3. | Joey Barros | 19 | 258.3 | 2000 | |
| Rene Mills | 19 | 193.7 | 2000 | ||
| 5. | Gerald Johnson | 17 | 249.0 | 2000 | |
| Jeeves Van Hooten | 17 | 237.7 | 2000 | ||
| Miguel Villalobos | 17 | 236.7 | 2000 | ||
| Aaron Bacon | 17 | 233.0 | 2000 | ||
| George Harmon | 17 | 224.0 | 2000 | ||
| 10. | Jose Valdovinos | 16 | 220.3 | 2000 | |
| 11. | Sammie Roberts | 15 | 258.3 | 2000 | |
| Keenan Brochu | 15 | 224.3 | 2000 | ||
| Christopher Partida | 15 | 223.7 | 2000 | ||
| Angelo Arroyo | 15 | 219.0 | 2000 | ||
| Sauron Evil | 15 | 204.0 | 2000 | ||
| Deangelo Rodarte | 15 | 200.7 | 2000 | ||
| 17. | Richard Hirsh | 14 | 254.0 | 2000 | |
| Brian Valero | 14 | 252.7 | 2000 | ||
| Armand Banuelos | 14 | 247.3 | 2000 | ||
| Kenneth Eshleman | 14 | 236.3 | 2000 | ||
| Nick Flowers | 14 | 235.7 | 2000 | ||
| David Evans | 14 | 229.7 | 2000 | ||
| Gregory Hart | 14 | 219.0 | 2000 | ||
| Darius Glover | 14 | 207.0 | 2000 | ||
| Marvin Arnott | 14 | 206.3 | 2000 | ||
| Francis Domenico | 14 | 200.3 | 2000 | ||
| Alfred Raskin | 14 | 185.7 | 2000 | ||
| 28. | Thomas Showers | 13 | 240.3 | 2000 | |
| Pedro Ceasar | 13 | 226.3 | 2000 | ||
| David Scoggin | 13 | 220.7 | 2000 | ||
| James Pineda | 13 | 211.7 | 2000 | ||
| Randy Kennedy | 13 | 202.3 | 2000 | ||
| John Demar | 13 | 189.0 | 2000 | ||
| Bernardo Rodriguez | 13 | 181.7 | 2000 | ||
| 35. | Sunny Bell | 12 | 245.0 | 2000 | |
| Paul Harrington | 12 | 237.0 | 2000 | ||
| Malik Meng | 12 | 235.7 | 2000 | ||
| Christopher Kearns | 12 | 231.7 | 2000 | ||
| Taira Korekiyo | 12 | 229.7 | 2000 | ||
| Richard Eaker | 12 | 229.7 | 2000 | ||
| Alfonzo Cortez | 12 | 224.0 | 2000 | ||
| Samuel Grijalva | 12 | 212.0 | 2000 | ||
| Timothy Buser | 12 | 210.3 | 2000 | ||
| Alfonso Arevalo | 12 | 203.0 | 2000 | ||
| Harry Swint | 12 | 202.3 | 2000 | ||
| Joe Phillips | 12 | 201.7 | 2000 | ||
| William Piccolo | 12 | 168.3 | 2000 | ||
| John Knighton | 12 | 87.3 | 2000 | ||
| 49. | Dustin Carrasquillo | 11 | 234.3 | 2000 | |
| Nick Weathers | 11 | 217.7 | 2000 | ||
| Freddy Estrada | 11 | 211.0 | 2000 | ||
| Clemente Carrero | 11 | 191.3 | 2000 | ||
| Beau Fletcher | 11 | 157.7 | 2000 | ||
| Donald Wingo | 11 | 148.7 | 2000 | ||
| Jose Rivero | 11 | 112.7 | 2000 | ||
| 56. | Dan Entrekin | 10 | 234.7 | 2000 | |
| Kelvin Palen | 10 | 218.7 | 2000 | ||
| Alan Yelverton | 10 | 210.7 | 2000 | ||
| Ron Yarbrough | 10 | 207.7 | 2000 | ||
| Robert Ford | 10 | 205.0 | 2000 | ||
| Tyrell Silvera | 10 | 201.0 | 2000 | ||
| Anthony Frey | 10 | 189.3 | 2000 | ||
| Justin Calvillo | 10 | 186.7 | 2000 | ||
| Brian Riojas | 10 | 185.0 | 2000 | ||
| Eric Song | 10 | 183.3 | 2000 | ||
| Joe Adams | 10 | 148.3 | 2000 | ||
| Douglas Elia | 10 | 144.0 | 2000 | ||
| Harry Griffin | 10 | 141.3 | 2000 | ||
| Michael Nickson | 10 | 108.0 | 2000 | ||
| 70. | Anthony Pilon | 9 | 221.7 | 2000 | |
| Robert Dwyer | 9 | 206.0 | 2000 | ||
| Wilton Nickle | 9 | 198.7 | 2000 | ||
| Richard Marker | 9 | 195.0 | 2000 | ||
| Steffen Conerly | 9 | 190.7 | 2000 | ||
| James Klein | 9 | 185.0 | 2000 | ||
| Nicholas Desantiago | 9 | 161.0 | 2000 | ||
| Ferdinand Lueras | 9 | 159.3 | 2000 | ||
| Thomas Paz | 9 | 153.0 | 2000 | ||
| Lenard Randazzo | 9 | 132.0 | 2000 | ||
| Ross Profitt | 9 | 109.3 | 2000 | ||
| Daniel Lane | 9 | 99.3 | 2000 | ||
| Jose Nunez | 9 | 82.0 | 2000 | ||
| Alex Meza | 9 | 78.3 | 2000 | ||
| Bernard Galdamez | 9 | 69.7 | 2000 | ||
| 85. | Sean Mullet | 8 | 219.0 | 2000 | |
| Thomas Waxman | 8 | 218.0 | 2000 | ||
| Ronnie Owens | 8 | 203.0 | 2000 | ||
| Santos Quinonez | 8 | 196.0 | 2000 | ||
| Mohammad Parker | 8 | 194.7 | 2000 | ||
| Jose Garcia | 8 | 193.3 | 2000 | ||
| Angelo Ambriz | 8 | 161.7 | 2000 | ||
| Marcelo Rojas | 8 | 155.3 | 2000 | ||
| Adrian Villicana | 8 | 150.0 | 2000 | ||
| Joel Garofalo | 8 | 147.3 | 2000 | ||
| Blaine Titsworth | 8 | 145.0 | 2000 | ||
| Connie Christensen | 8 | 142.3 | 2000 | ||
| Stephen Mcjunkin | 8 | 131.3 | 2000 | ||
| Vincent Marguez | 8 | 105.7 | 2000 | ||
| Mohammad Montalvo | 8 | 102.0 | 2000 | ||
| Manuel Campos | 8 | 91.3 | 2000 |
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