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| Single Post-Season Wins Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Wins | IP | Year | Team | Career Leaderboard |
| 1. | Sauron Evil | 3 | 23.0 | 2000 | PEN | |
| Vincent Marguez | 3 | 13.7 | 2000 | PEN | ||
| 3. | Jose Valdovinos | 2 | 28.0 | 2000 | PEN | |
| Jeeves Van Hooten | 2 | 26.0 | 2000 | WAS | ||
| Brian Valero | 2 | 23.7 | 2000 | MON | ||
| Armand Banuelos | 2 | 20.0 | 2000 | MON | ||
| Tyrell Silvera | 2 | 15.7 | 2000 | LOU | ||
| Darius Glover | 2 | 15.0 | 2000 | LOU | ||
| Steven Stockwell | 2 | 10.3 | 2000 | PEN | ||
| 10. | Richard Eaker | 1 | 25.7 | 2000 | MON | |
| Keenan Brochu | 1 | 23.7 | 2000 | MON | ||
| Gerald Johnson | 1 | 23.0 | 2000 | PEN | ||
| Ron Yarbrough | 1 | 12.7 | 2000 | WAS | ||
| Malcolm Yokum | 1 | 8.7 | 2000 | WAS | ||
| Leo Quintana | 1 | 8.3 | 2000 | WIS | ||
| Jeffrey Cargo | 1 | 8.0 | 2000 | DC | ||
| Abram Barboza | 1 | 8.0 | 2000 | WAS | ||
| Dale Vance | 1 | 7.3 | 2000 | WAS | ||
| John Charity | 1 | 7.0 | 2000 | WIS | ||
| Gregory Hart | 1 | 6.0 | 2000 | CAL | ||
| Michael Odom | 1 | 3.7 | 2000 | MON | ||
| Earnest Hunziker | 1 | 2.3 | 2000 | LOU |
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